Antibody refers to the protective protein produced by the body due to the stimulation of the antigen. It is a large Y-shaped protein secreted by plasma cells (effector B cells) that is used by the immune system to identify proteins from neutralizing foreign substances such as bacteria and viruses. It is only found in vertebrates in the blood and the cell membrane surface of B cells. Antibodies specifically recognize the target on the specific antigen.
Both two heavy chains and two light chains of the antibody molecule fold into several spherical domains, each exercising its corresponding function. The light chain has two domains, VL and CL; the heavy chains of IgG, IgA and IgD have four domains, VH, CH1, CH2 and CH3; and the heavy chain of IgM and IgE has five domains, namely one more CH4 domain. Antibodies can be classified into mAbs and pAbs based on the specificity of their recognition site. Abvigen can prepare mAbs and pAbs with high efficiency and high affinity for different species.
