What are magnetic beads?
Magnetic beads are usually composed of iron oxides, such as magnetite (Fe3O4), which have superparamagnetic properties. In the presence of a magnetic field, it exhibits magnetic properties, and no residual magnetism once the field is removed. This property is dependent on the size of the particles in the beads, and enables the beads to be separated in suspension, along with anything they are bound to. Since they don¡¯t attract each other when magnetic field removed, they can be used without any concern about unwanted clumping. The magnetic beads technology has a lot of application fields. It can be utilized for the manipulation of biological material, including cells, nucleic acids, proteins microorganisms.
How magnetic separation and extraction works?
In biology, magnetic beads provide a simple and reliable method of purifying different types of biomolecule, including protein, genomic DNA, plasmids, mitochondrial DNA, and RNA.
A key advantage to using magnetic beads is that you can extract nucleic acids and other biomolecules directly from a crude sample, and from a variety of different types of sample, with minimal processing.